Event

Dr. Oliver interviewed by BCRF at AACR 2018

We attended AACR 2018 this year in Chicago and had the opportunity to present our work during the poster session. I presented the most recent results in the development of our blood brain barrier on a chip system that we are using to parenthetically characterize different cancer cells and measure their impact on the blood brain barrier.

During the session I was fortunate to get to share our work with one of our sponsers the Breast Cancer Research Foundation (BCRF).

https://www.bcrf.org/blog/aacr-2018-highlights-novel-approaches-treating-brain-metastasis-metastatic-breast-cancer

Dr. Oliver speaking at AACR 2018.

Organ-on-a-chip: Blood brain niche (um-BBN) microfluidic device and algorithms to aid diagnosis of brain metastatic potential of breast cancer

C. Ryan Oliver et al. 2018 Keystone Symposium Organ on a Chip.

We presented work continued work on the blood brain barrier platform but were fortunate to get to learn from other experts in organ-on-a-chip systems. It was an honor to get to discuss the field and develop a roadmap for integrating academia, regulation and industry into the planning process for organ-on-a-chip systems so that they can solve real world problems.

Special thanks to our sponsors BCRF and the National institute of health.

University of Michigan Cancer Center Symposium 2017

We will be presenting work about a blood brain niche on a chip that have developed to understand clonal variation in breast cancer cells that metastasis to the brain.  This is a great event to meet a variety of cancer researchers and understand how biology, materials and microfluidics can be leveraged to solve translational problems.

Metastasis from the primary tumor site to the brain is the most lethal complication of advanced cancer.  15% of breast cancers metastasize in the brain with a median survival of 5-14 months depending on the subtype.  Therefore, it is critical to identify when a tumor has […]

Progress towards blood brain barrier chip to be presented at AACR 2017

We will be attending the annual AACR (American Association for Cancer Research) meeting in D.C. April 1-5 to present our progress towards an organ on a chip model to study breast cancer metastasis in the brain.

This work provides an important foundation to apply microfluidics in translational identification of breast cancer clones that may contribute to aggressive brain metastasis.  Please join us and I look forward to meeting you.

MBSTP Seminar Sept. 7 on additive manufacturing of cells and microbeads

Dr. C. Ryan Oliver
Department of Internal Medicine and Bioengineering, University of Michigan

Tuesday, 9/27/2016 at 11:30am
Boulevard Room at Pierpont Commons

 
An additive manufacturing approach to printing cells and microbeads within digitally addressed hydrogel matrices
 
Rapid prototyping of new hydrogel-based structures, including tissue scaffolds, organs-on-chip, and hybrid bioelectronic materials, requires flexible fabrication techniques capable of positioning multiple materials in 2D and 3D with micro-scale resolution and accuracy. Despite their impressive accomplishments, current methods for micro-scale additive manufacturing are limited to a single material (e.g. projection micro stereolithography) or require sequential or parallel use of multiple nozzles to deposit different materials.  An alternative approach would […]

Progress towards metastasis chip to be presented at AACR April 16-20

We will be attending the annual AACR (American Association for Cancer Research) meeting in New Orleans to present our progress towards an organ on a chip model to study breast cancer metastasis in the brain.

This work is being presented by Megan Altemus and was originally lead by Brendan Leung.  I hope to see you there or send me a message and I’ll be happy to discuss what we are working on.

 

 

Discrete Object Additive Manufacturing (DOAM): Digital Three-Dimensional Printing of Cells and Microbeads within Hydrogel Matrices

At the Materials Research Society (MRS) annual meeting (2015) I will be presenting my work titled: Discrete Object Additive Manufacturing (DOAM): Digital Three-Dimensional Printing of Cells and Microbeads within Hydrogel Matrices  

Authors: C. R. Oliver, A. J. Hart,

Symposium: C3.09

Location: Hynes Level 3, Room 305

Time: Dec 1 (Tuesday): 11:30 AM to 11:45 AM

 

I hope to see you there and have a lively discussion.

 

Scalable Fabrication of Stimuli-Responsive Liquid Crystalline Polymer Microstructures by Replica Molding

At the Materials Research Society (MRS) annual meeting (2015) Hangbo Zhao will be presenting our work titled:  Scalable Fabrication of Stimuli-Responsive Liquid Crystalline Polymer Microstructures by Replica Molding.

Authors: Hangbo Zhao, Jeong Jae Wie, Davor Copic, C. Ryan Oliver, Alvin W. Orbaek, Sanha Kim, and A. John Hart

Presentation: Oral

Symposium: Y. Shape Programmable Materials  

Location: Hynes, Level 1, Room 105

Time: December 1, 2015 (Tuesday)  2:15-2:30 pm

 

I hope to see you there and have a lively discussion.

Join us at the 2015 C. elegans International Conference

Eleni Gourgou and I will be presenting “Real-time behavioral study of C. elegans by dynamic in situ photopatterning of hydrogel assays” at the 2015 C. elegans International Conference.  Hope to see you there June 24-28.

http://www.genetics-gsa.org/celegans/2015/

Abstract:

Real-time behavioral study of C. elegans by dynamic in situ photopatterning of hydrogel assays

Eleni Gourgou1, 2*, C. Ryan Oliver1, 3*, Daphne Bazopoulou1, Nikos Chronis1, 4, A. John Hart3

1Mechanical Engineering, University of Michigan, Ann Arbor, MI

2Internal Medicine, Division of Geriatrics, Medical School, University of Michigan, Ann Arbor, MI

3Mechanical Engineering and Laboratory for Manufacturing and Productivity, Massachusetts Institute of Technology, Cambridge, MA

4Biomedical Engineering, University of Michigan, Ann Arbor, MI

*Equal […]

Graduation Day: Thank you all and happy graduation day

Today was the Winter UofM Graduation Ceremony.  Congratulations to all the graduates on their accomplishments.  It was electric and the speaker, Charles F. Bolden Jr. was fantastic.